The Genetic Rescue Foundation Blog

Over 5000 base pairs were inserted into mammalian cells using a simplified end joining process

Researchers have shown that a site specific double strand break (DSB) generated both in the genome and the donor plasmid using the CRISPR-Cas9 system can be efficiently used to target ∼5 kb plasmids into mammalian genomes via nonhomologous end… Read More

Scientists resurrect woolly mammoth gene in human cell

Scientists “resurrected” a mammoth gene by transplanting it into a human kidney cell in the lab. The gene, called TRPV3, is known to affect temperature sensation and hair growth regulation. When they added the mammoth TRPV3 gene to… Read More

Are We Really 99% Chimp?

A great simplified overview of the complexities involved in genome comparison.

Fossilized dinosaur blood (but no genetic material)

The fossilized blood cells were found in the claw of an a unidentified theropod (a dinosaur group which includes T. rex and velociraptor). The collagen was found in several other bones, including ribs from unknown species or genuses…. Read More

How to Clone a Mammoth: The Science of De-Extinction – with Beth Shapiro

Oliver A. Ryder on designing the destiny of biological diversity

The question “how far should we go to bring back a lost species?” opens a deeper discussion that requires us to consider what kind of world we want now and for the future. In answering, I am considering… Read More

Complete Woolly Mammoth Genome Sequenced

An international team of scientists has sequenced the complete genome of the woolly mammoth. A US team is already attempting to study the animals’ characteristics by inserting mammoth genes into elephant stem cells. They want to find out… Read More